Assessment schedule for intervention group
| Visit | Blood test | Urine test | Zoledronic acid (infused over 30 mins) | X-rays, DXA and MRI | 25(OH) D level | Hip range of motion | Faces Pain Scale | Questionnaires: Harris hip score and PODCI |
| Screening | X | X | X | X | X | X | X | |
| First infusion | X | X | X | |||||
| 48 hours postinfusion | X | |||||||
| 72 hours postinfusion | X | |||||||
| 3 months (second infusion) | X | X | X | X | ||||
| 6 months (third infusion) | X | X | X | X | X | X | X | |
| 9 months (fourth infusion) | X | X | X | X | ||||
| 12 months (fifth infusion) | X | X | X | X | X | X | X | X |
| 18 months | X | |||||||
| 24 months | X | X | X | X | X |
DXA, Dual-energy X-ray absorptiometry; PODCI, Global Paediatric Outcomes Data Collection Instrument questionnaires.