Survival rates have greatly improved in recent years for infants of borderline viability;
however, these infants remain at risk of developing a wide array of complications, not only in …

Background Infants born preterm are at increased risk of developing cognitive and motor
impairment compared with infants born at term. Early developmental interventions have …

Background Epidemiological and basic science evidence suggests that magnesium
sulphate before birth may be neuroprotective for the fetus. Objectives To assess the effects …

Background Methylxanthines reduce the frequency of apnea of prematurity and the need for
mechanical ventilation during the first seven days of therapy. It is uncertain whether …

Background Bronchopulmonary dysplasia is associated with ventilation and oxygen
treatment. This randomized trial investigated whether nasal continuous positive airway …

Background Methylxanthine therapy is commonly used for apnea of prematurity but in the
absence of adequate data on its efficacy and safety. It is uncertain whether methylxanthines …

ContextThe outcome into school age of regional cohorts of children born in the 1990s with
birth weights less than 1000 g (extremely low birth weight, ELBW) or earlier than 28 weeks' …

Objective To determine the effectiveness and safety of moderate whole-body hypothermia in
newborns with hypoxic-ischemic encephalopathy born in hospitals with and without …

ContextPrenatal magnesium sulfate may reduce the risk of cerebral palsy or death in very
preterm infants. ObjectiveTo determine the effectiveness of magnesium sulfate given for …

Objective. To determine the frequency, nature, and severity of executive dysfunction (EDF) at
8 years of age in extremely low birth weight (ELBW)/very preterm infants who were born in …