Cortical bone structure is a crucial determinant of bone strength, yet for many years studies
of novel genes and cell signalling pathways regulating bone strength have focused on the …

Measurements of insulin-like growth factor-I (IGF-I) are useful not only for diagnosis and
management of patients with growth hormone (GH)-related disorders but also for assessing …

Nail–patella syndrome (NPS) is an autosomal-dominant disease caused by LMX1B
mutations and is characterized by dysplastic nails, absent or hypoplastic patellae, elbow …

1The Japanese Society for Pediatric Endocrinology, Kyoto, Japan 2Department of
Pediatrics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan …

Turner syndrome (TS) is a chromosomal disorder affecting females characterized by short
stature and gonadal dysgenesis. Untreated girls with TS reportedly are approximately 20-cm …

Kenny–Caffey syndrome (KCS) is a rare dysmorphologic syndrome characterized by
proportionate short stature, cortical thickening and medullary stenosis of tubular bones …

Bone strength is determined by its dense cortical shell, generated by unknown mechanisms.
Here we use the Dmp1Cre: Socs3f/f mouse, with delayed cortical bone consolidation, to …

The prevalence of vitamin D deficiency, presenting as hypocalcemic seizures or rickets in
children, is increasing worldwide due to insufficient vitamin D intake and lack of exposure to …

Background Nail–patella syndrome (NPS) is a rare autosomal-dominant disorder caused by
LMX1B mutation. In patients with the renal lesions typical of NPS without skeletal or nail …

This study examined whether maternal nutritional intake and breast milk macronutrient
content influence the weight of breastfed infants. We investigated 129 healthy mothers with …