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Respiratory syncytial virus prevalence in children admitted to five Kenyan district hospitals: a cross-sectional study
  1. Jacqueline Le Geyt1,2,
  2. Stephanie Hauck3,
  3. Mark Lee2,
  4. Jennifer Mackintosh2,
  5. Jessica Slater2,
  6. Duke Razon2,
  7. Bhanu Williams4
  1. 1 Paediatric Emergency Department, Royal Alexandra Children’s Hospital, Brighton, UK
  2. 2 Global Links Volunteer, Royal College of Paediatrics and Child Health, London, UK
  3. 3 Paediatric Department, Nanyuki Teaching and Referral Hospital, Nanyuki, Kenya
  4. 4 Paediatric Department, London North West Healthcare NHS Trust, London, UK
  1. Correspondence to Dr Jacqueline Le Geyt; jacquilegeyt{at}hotmail.com

Abstract

Acute respiratory infections (ARIs) are a leading cause of under-five mortality globally. In Kenya, the reported prevalence of respiratory syncytial virus (RSV) infections in single-centre studies has varied widely. Our study sought to determine the prevalence of RSV infection in children admitted with ARI fulfilling the WHO criteria for bronchiolitis. This was a prospective cross-sectional prevalence study in five hospitals across central and highland Kenya from April to June 2015. Two hundred and thirty-four participants were enrolled. The overall RSV positive rate was 8.1%, which is lower than in previous Kenyan studies. RSV-positive cases were on average 5 months younger than RSV-negative cases.

  • tropical paediatrics
  • respiratory
  • epidemiology

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Footnotes

  • Contributors All persons listed as authors made substantial contributions to the conception of the work or interpretation of data for the work. Drafting the work or revising it critically for important intellectual content. Final approval of the version to be published. Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

  • Competing interests None declared.

  • Ethics approval Ethical approval was obtained from Princeton University Institutional Review Board (Protocol # 6760) and Kenya Medical Research Institute. KEMRI/RES/7/3/1.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Collaborators Mr Peter Nash, Dr Sammy Kilonzo, Dr Grace Akechm, Dr Lydia Thuranira.

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