Neurodevelopment in 29 normocephalic children with in utero exposure to Zika virus (ZIKV) was evaluated by the Bayley Scales of Infant and Toddler Development-Third Edition. Ten (35%) infants presented neurodevelopment delay. Language, cognitive and motor delays were identified in 9 (31%), 4 (14%) and 1 (3%) infants, respectively. Children exposed to ZIKV in utero must undergo careful evaluations for the early detection of any neurodevelopment delays in order to implement prompt intervention.
- congenital infection
- Zika virus
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AXA and ICdS contributed equally.
Contributors ICdS, AXA and LCJA contributed to study design, writing of the manuscript and data analysis. AVF, JCdO, JVVO, BLdA and IAA contributed to the enrolment of participants in the study, reviewed the medical records and clinical evaluations.
Funding CNPq-National Council for Scientific and Technological Development (443875/2018-9) and PPSUS/BA-FAPESB003/2017/SESAB/CNPq/MS (5125/2017).
Competing interests None declared.
Patient consent for publication Not required.
Ethical approval This study was approved by the Institutional Review Board of the Oswaldo Cruz Foundation (IGM-FIOCRUZ) (protocol number 1.935.854/2016).
Provenance and peer review Not commissioned; externally peer reviewed.
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