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P68 What is the evidence for increased cardiovascular disease risk in children and young people with emotional mental health disorders?
  1. A Zapiti,
  2. LD Hudson
  1. Institute of Child Health, University College London, London, UK


Aims Contemporary pathological processes leading to cardiovascular disease (CVD) are known to begin in childhood and young people (CYP), and this can be increased in a number of disease states. It is well established that mental health disorders in adults are strongly linked to CVD with increased associated mortality. Less is known about the associations between CVD risk and mental health disorders in CYP; and it is unclear whether CYP with mental health disorders have higher rates of conventional, detectable CVD risk factors (such as dyslipidaemia), or contemporary pathological processes (such as arterial stiffening). Furthermore, this important question has never been systematically reviewed. We hypothesized that CYP with emotional mental health disorders (depression or anxiety) would have higher rates of CVD risk.

Methods We performed a systematic review of the literature using PRISMA guidelines. PubMed, PsychINFO, Web of Science and Embase were searched from inception to May 2019. Searches identified papers studying associations between CVD risk (contemporary CVD risk markers such as blood pressure, lipids, insulin resistance, central adiposity; established measures of arterial stiffening; or later disease outcomes) and common emotional mental health disorders (depression or anxiety) in CYP. Studies examining obesity and mental health disorders alone were excluded.

Results Results will be presented in narrative format, separated by individual risks and mental health disorder.

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