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5 CGM real world data in regional experience
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  1. Mohammed Yahia Alharbi
  1. Consultant Paediatric Endocrinologist, KSA

Abstract

Aim Measuring blood glucose level is crucial to type 1 diabetes (T1D) management and prevention of associated complications. Flash glucose monitoring, or continuous glucose monitoring, facilitates effective glycaemic control and can lower the cost burden associated with laboratory glycated haemoglobin (HbA1c) evaluation, severe hypoglycaemic events (SHEs), and diabetic ketoacidosis (DKA) rates. We aimed to assess the clinical benefit and hence the cost-savings associated with the use of flash glucose monitoring for children with T1D in the Kingdom of Saudi Arabia (KSA).

Methods Our study started by measuring the outcome of using FGM in regards to diabetes control then A model was designed to estimate the annual costs of SHEs and DKA management and laboratory HbA1c testing in KSA. Base case and one-way sensitivity analyses were used to calculate the cost-effectiveness of flash glucose monitoring in two scenarios based on DKA prevalence rates (scenario one, 65.4%; scenario two, 20.6%).

Results Their was clear and measured improvement in the children with type 1 diabetes in form of increase time in range (TIR), decrease in sever hypoglycaemia events (SHEs), decrease DKA Episodes and improvement of HbA1c, as well as Potential annual cost-savings associated with the use of flash glucose monitoring accrued to 14,134 SAR (3,767 USD) and 10,370 SAR (2,763 USD) per person in scenarios one and two, respectively. This was associated with a lower incidence of T1D-related clinical complications and sustained ideal glycaemic levels. Additionally, analyses revealed that the most sensitive parameter of the model was laboratory HbA1c reduction.

Conclusions In our studies, the use of the flash glucose monitoring system has demonstrated great improvement in Diabetes Control and potential cost-savings when managing T1D in KSA and is a favourable method of glucose monitoring in T1D. However, additional clinical studies are warranted to further investigate the precise cost-effectiveness of the flash glucose monitoring system in the management of T1D.

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