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PP-102 The course of community-acquired pneumonia in children, depending on vaccination
  1. Kuryazova Sharofat Masharipovna,
  2. Khudaynazarova Salomat Ruzibaevna,
  3. Dergunova Galina Evgenevna,
  4. Toshmetova Bakhtiniso Rustoevna Kuryazova,
  5. Kuryazova,
  6. Dergunova,
  7. Toshmetova
  1. Tashkent Pediatric Medical Institute, Uzbekistan


Community-acquired pneumonia (CAP), despite advances in diagnosis, treatment and vaccine prevention, remains a major problem in pediatrics.

Aim To determine the clinical course of community-acquired pneumonia depending on vaccine prophylaxis in preschool children.

Material and Method We examined - 120 children aged 3 -7 years with Out-of-hospital pneumonia. The children were divided into 2 groups: Group 1 - 78 (65%); who did not receive pneumococcal vaccine; Group 2 - 42(35%) children vaccinated with pneumococcal vaccine.

Results Analysis of the results obtained, Severe course of community-acquired pneumonia with febrile hyperthermia was observed in 42 children (53.9%) of group 1, and with subfebrile temperature with a mild course of VP - in 46.1%. In children of this group, 2-sided focal-drain pneumonia was diagnosed in 56.4%, right-sided lung lesion - 34.5%, left-sided lesion - 10.0%. In the group of unvaccinated children, 87.5% had a productive cough and 81.8% had shortness of breath. In vaccinated children, right-sided focal pneumonia was diagnosed in 89.0%, and 2-sided focal-drain pneumonia in 11.0% of cases. Severe acute pneumonia in this group was detected in 54.5% and was characterized by symptoms of dysfunction of the respiratory and circulatory systems, 3 children had a minimal degree of heart failure. Comorbid diseases in children of group 1 were manifested by atopic dermatitis (44.8%), irritable bowel syndrome (38.9%), residual rickets (23.6%), and in children of 2-group (figure 1).

Abstract PP-102 Figure 1

Clinical symptoms in children with out-of-hospital pneumonia

Comorbid diseases in children of group 1 were manifested by atopic dermatitis (44.8%), irritable bowel syndrome (38.9%), residual rickets (23.6%), and in children of 2-group atopic dermatitis (28.7%). In unvaccinated children at 2 and 3 years of life there were frequent ARIs with otitis (24.7%), and in vaccinated children this figure was 5.6%. (Figure 2).

Abstract PP-102 Figure 2

Comorbid pathologies in children with out-of-hospital pneumonia

Abstract PP-102 Table 1

Clinical characteristics of pneumonia

Conclusions In children vaccinated according to the calendar against pneumococcal infection, the course of community-acquired pneumonia was more favorable and in most cases uncomplicated, and they also had 2 times fewer acute respiratory infections. Thus, vaccination of children against pneumococcal infection should be mandatory, which will reduce child mortality.

  • Children
  • pneumonia
  • Vitamin D

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