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PP-102 The course of community-acquired pneumonia in children, depending on vaccination
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  1. Kuryazova Sharofat Masharipovna,
  2. Khudaynazarova Salomat Ruzibaevna,
  3. Dergunova Galina Evgenevna,
  4. Toshmetova Bakhtiniso Rustoevna Kuryazova,
  5. Kuryazova,
  6. Dergunova,
  7. Toshmetova
  1. Tashkent Pediatric Medical Institute, Uzbekistan

Abstract

Community-acquired pneumonia (CAP), despite advances in diagnosis, treatment and vaccine prevention, remains a major problem in pediatrics.

Aim To determine the clinical course of community-acquired pneumonia depending on vaccine prophylaxis in preschool children.

Material and Method We examined - 120 children aged 3 -7 years with Out-of-hospital pneumonia. The children were divided into 2 groups: Group 1 - 78 (65%); who did not receive pneumococcal vaccine; Group 2 - 42(35%) children vaccinated with pneumococcal vaccine.

Results Analysis of the results obtained, Severe course of community-acquired pneumonia with febrile hyperthermia was observed in 42 children (53.9%) of group 1, and with subfebrile temperature with a mild course of VP - in 46.1%. In children of this group, 2-sided focal-drain pneumonia was diagnosed in 56.4%, right-sided lung lesion - 34.5%, left-sided lesion - 10.0%. In the group of unvaccinated children, 87.5% had a productive cough and 81.8% had shortness of breath. In vaccinated children, right-sided focal pneumonia was diagnosed in 89.0%, and 2-sided focal-drain pneumonia in 11.0% of cases. Severe acute pneumonia in this group was detected in 54.5% and was characterized by symptoms of dysfunction of the respiratory and circulatory systems, 3 children had a minimal degree of heart failure. Comorbid diseases in children of group 1 were manifested by atopic dermatitis (44.8%), irritable bowel syndrome (38.9%), residual rickets (23.6%), and in children of 2-group (figure 1).

Abstract PP-102 Figure 1

Clinical symptoms in children with out-of-hospital pneumonia

Comorbid diseases in children of group 1 were manifested by atopic dermatitis (44.8%), irritable bowel syndrome (38.9%), residual rickets (23.6%), and in children of 2-group atopic dermatitis (28.7%). In unvaccinated children at 2 and 3 years of life there were frequent ARIs with otitis (24.7%), and in vaccinated children this figure was 5.6%. (Figure 2).

Abstract PP-102 Figure 2

Comorbid pathologies in children with out-of-hospital pneumonia

Abstract PP-102 Table 1

Clinical characteristics of pneumonia

Conclusions In children vaccinated according to the calendar against pneumococcal infection, the course of community-acquired pneumonia was more favorable and in most cases uncomplicated, and they also had 2 times fewer acute respiratory infections. Thus, vaccination of children against pneumococcal infection should be mandatory, which will reduce child mortality.

  • Children
  • pneumonia
  • Vitamin D

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