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  • OP-078 Comparison of extracorporeal membrane oxygenation outcomes in children between two 5-year periods in a single tertiary center in Turkey

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OP-078 Comparison of extracorporeal membrane oxygenation outcomes in children between two 5-year periods in a single tertiary center in Turkey
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  1. Mert Kaan Coşkun1,
  2. Tanıl Kendirli2,
  3. Merve Havan2,
  4. Anar Gurbanov2,
  5. Burak Balaban2,
  6. Hasan Özen2,
  7. Fevzi Kahveci2,
  8. Hacer Uçmak2,
  9. Tayfun Uçar3,
  10. Mehmet Gökhan Ramoğlu3,
  11. Zeynep Eyileten4,
  12. Nur Dikmen4
  1. 1Ankara University, Faculty of Medicine, Department of Pediatrics
  2. 2Ankara University, Faculty of Medicine, Divisions of Pediatric Critical Care
  3. 3Ankara University, Faculty of Medicine, Department of Pediatric Cardiology
  4. 4Ankara University, Faculty of Medicine, Department of Pediatric Cardiovascular Surgery

Abstract

Aim Extracorporeal Membrane Oxygenation is a treatment method that provides life-sustaining gas exchange and hemodynamic support. We aimed to evaluate outcomes of ECMO in Ankara University Faculty of Medicine PICU over 10 years by comparing the first and second 5-year periods. Schematic of ECMO unit was shown in figure 1.

Abstract OP-078 Figure 1
Abstract OP-078 Figure 1

ECMO Unit. Schematic of Pediatric ECMO Unit1

Material and Method ECMO patients’ data in Ankara University PICU between January 2014 and July 2023 were retrospectively gathered and compared

Results 120 patients over 110 months were included in the study. ECMO was implemented in 69 patients in the first half and 51 in the second half. 35 patients (50.7%) were female and 34 patients (49.3%) were boys in the first half, whereas, 24 patients (47.1%) were female and 27 (52.9%) were male in the second half. The mean age of the patients was 84±80.6 months. In the first half, 15 patients (21.7%) had cardiomyopathy, 6 (8.6%) myocarditis, 12 (17.4%) ECPR, 9 (13%) failure to separate from CBP after cardiac surgery, 7 (10.1%) low cardiac output syndrome after cardiac surgery, 5 (7.2%) refractory septic shock, 9 (13%) ARDS, and 7 (9.8%) other indications. In the second half, 11 patients (21.6%) had cardiomyopathy, 1 (3.9%) had myocarditis, 15 (29.4%) had ECPR, 10 (19.6%) failed to separate from CBP, 3 (5.9%) low cardiac output syndrome, 3 (5.9%) refractory septic shock, and 8 (15.7%) ARDS. The average duration of ECMO was 11.13± 11.80 (1–56) days. ECMO support was successfully implemented and weaned in 30 patients in the first and 19 patients in the second half. ECMO survival rates are 31.3% in the first half and 27.4% in the second half. ECMO Indications for patient groups are shown in table 1.

View this table:
Abstract OP-078 Table 1

Indications of ECMO patients

Conclusions ECMO treatment for the underlying cause should be kept in mind for pediatric patients with a high risk of death who do not respond to high-level conventional treatments. Successful results can be achieved by choosing the appropriate method and good complication management at experienced centres

Reference

  1. Valencia E, Nasr VG. Updates in pediatric extracorporeal membrane oxygenation. J Cardiothorac Vasc Anesth 2020;34(5):1309–1323.

  • Extracorporeal membrane oxygenation (ECMO)
  • Cardiogenic shock
  • Extracorporeal Cardiopulmonary Resuscitation

https://doi.org/10.1136/bmjpo-2024-EPAC.77

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