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OP-128 Evaluation of interictal anxiety level and anxiety-related factors in children with epilepsy using anti-seizure drugs
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  1. Buse Yılmaz1,
  2. Ayşenur Coşkun2,
  3. Canan Üstün2,
  4. Mutluay Arslan2,
  5. Bülent ÜNAY2
  1. 1University of Health Sciences Türkiye, Gülhane Faculty of Medicine, Department of Pediatrics, Ankara, Turkey
  2. 2University of Health Sciences Türkiye, Gülhane Faculty of Medicine, Department of Pediatric Neurology, Ankara, Türkiye

Abstract

Aim Aim of study is evaulationing the effects of medical and sociodemographic factors on the level of interictal anxiety in children with epilepsy taking anti-seizure medication.

Material and Method The study included 136 patients aged 8–18 years, who were followed with the diagnosis of epilepsy in Gülhane Training and Research Hospital Pediatric Neurology Outpatient Clinics between December 1, 2022 and March 31, 2023. Revised Child Anxiety and Depression Scale Child and Parents Version (RCADS) were used. The correlation between the variables and the scale scores was evaluated.

Results It was found that among children with epilepsy, having more siblings was statistically associated with higher levels of anxiety. Children with epilepsy whose mothers did not work were found to have higher separation anxiety. Total anxiety sensitivity level was found to be higher in children with generalized seizures than in children with focal seizures. Patients with focal epileptiform activity on EEG had a higher total anxiety level and generalized anxiety disorder than patients with multifocal, generalized activity and no pathology on EEG. Generalized anxiety disorder was found to be higher in those who had side effects. In our study, no relation was found between anxiety level and drug type, seizure type, epilepsy type, epilepsy syndrome, diagnosis time and last seizure time.

Conclusions This study is one of the few studies in which the level of anxiety and the factors affecting anxiety in children with the diagnosis of epilepsy and using anti-seizure medication were evaluated in a comprehensive way, both medically and sociodemographically. It has been found that there is a correlation between the number of siblings, the mother’s employment status, where epileptiform activity is seen on EEG, the side effects of anti-seizure medication and anxiety level in children with epilepsy who are taking anti-seizure medication. Further studies can be done for other variables for which no significant relationship can be detected.

  • anti-seizure drugs
  • anxiety
  • children
  • epilepsy
  • anticonvulsant drugs

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