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PP-004 Mold as a cause of allergic rhinitis
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  1. Julia Levina1,
  2. Vera Kalugina1,
  3. Elena Vishneva1,
  4. Anna Alekseeva2,
  5. Kamilla Efendieva1,
  6. Konstantin Volkov2,
  7. Leyla Namazova-Baranova1
  1. 1Pirogov Russian National Research Medical University, Moscow, Russia
  2. 2Pediatrics and Child Health Research Institute of Petrovsky National Research Center of Surgery, Moscow, Russia

Abstract

Aim Allergic rhinitis is the most common allergic disease in children and adults all over the world. Mold is one of the causes of allergic rhinitis, following pollen, animal and house dust mites allergens.

Material and Method This is a case report of an 11-year-old girl with persistent symptoms of allergic rhinitis and atopic eczema.

Results During the first year of life no signs of atopy were observed. From 1.5 years the patient occasionally experienced skin rash with moderate itching. She was diagnosed with ‘Atopic eczema,’ exacerbations occur several times a year. Since the age of 7, the child has complained of frequent nasal congestion, sneezing and itchy nose. She has taken antihistamines and intranasal corticosteroids with some effect. The girl has been involved in equestrian sports since the age of 3, currently participating training three times a week, also she has a hamster as a pet in the apartment. She notices a worsening of allergic rhinitis symptoms in the summer and in the stable. Previously, the patient was examined by allergist the sensitization to horse and other animal, pollen, and house dust mites allergens was not detected. Total IgE was 3000 IU/ml, and helminthiasis was ruled out. She had a single episode of acute respiratory viral infection with wheezing. It was decided to conduct allergy testing using the ALEX2 allergochip at the clinic. A high level of monosensitization to the mold allergen Alternaria alternata Alt a 1 – 50 kUa/l was identified. Exacerbations of rhinitis in the stable are likely associated with a humid microclimate and a large amount of mold in the horse’s forage.

Conclusions Component-resolved diagnostics using an ALEX2 allergochip is useful in identifying rare causes of allergies in children. Knowing the allergen helps develop personalized treatment plan for allergic diseases and prevent exacerbations.

  • allergic rhinitis
  • ALEX2 allergochip
  • Component-resolved diagnostics
  • sensitization to the mold
  • children

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