TY - JOUR T1 - Acute pancreatitis in children – morbidity and outcomes at 1 year JF - BMJ Paediatrics Open JO - BMJ Paediatrics Open DO - 10.1136/bmjpo-2022-001487 VL - 6 IS - 1 SP - e001487 AU - A Bhanot AU - AA Majbar AU - Toby Candler AU - LP Hunt AU - E Cusick AU - Paul R V Johnson AU - Julian PH Shield Y1 - 2022/07/01 UR - http://bmjpaedsopen.bmj.com/content/6/1/e001487.abstract N2 - Objective To establish short-term and medium-term complications 1-year postdiagnosis, of acute pancreatitis (AP) in children aged 0–14 years.Design One-year follow-up of a prospective monthly surveillance of new cases of AP in children under 15 years through the British Paediatric Surveillance Unit (BPSU) from April 2013 to April 2014.Setting A monthly surveillance of >3700 consultant paediatricians and paediatric surgeons in the UK and Ireland using the BPSU.Patients Children aged 0–14 years with a new diagnosis of AP.Main outcome measures The outcomes following AP, including the incidence of complications and comorbidity at diagnosis and at 1 year.Results Of the 94 new confirmed cases of AP identified in the UK during the study period, 90 cases (96%) were included in the 1-year follow-up. 30 patients (32%) developed further episode(s) of AP. Over one-fifth of patients developed one or more major complication. At initial admission, the most common of these was pancreatic necrosis (n=8, 9%), followed by respiratory failure (n=7, 7%). Reported complications by 1 year were pseudocyst formation (n=9, 10%), diabetes requiring insulin therapy (n=4, 4%) and maldigestion (n=1, 1%). At 1-year postdiagnosis, only 59% of children made a full recovery with no acute or chronic complications or recurrent episodes of AP. Two patients died, indicating a case fatality of ~2.0%.Conclusions AP in childhood is associated with significant short-term and medium-term complications and comorbidities including risk of recurrence in approximately a third of cases.Data may be obtained from a third party and are not publicly available. ER -