PT  - JOURNAL ARTICLE
AU  - A Bhanot
AU  - AA Majbar
AU  - Toby Candler
AU  - LP Hunt
AU  - E Cusick
AU  - Paul R V Johnson
AU  - Julian PH Shield
TI  - Acute pancreatitis in children – morbidity and outcomes at 1 year
AID  - 10.1136/bmjpo-2022-001487
DP  - 2022 Jul 01
TA  - BMJ Paediatrics Open
PG  - e001487
VI  - 6
IP  - 1
4099  - http://bmjpaedsopen.bmj.com/content/6/1/e001487.short
4100  - http://bmjpaedsopen.bmj.com/content/6/1/e001487.full
SO  - BMJ Paediatrics Open2022 Jul 01; 6
AB  - Objective To establish short-term and medium-term complications 1-year postdiagnosis, of acute pancreatitis (AP) in children aged 0–14 years.Design One-year follow-up of a prospective monthly surveillance of new cases of AP in children under 15 years through the British Paediatric Surveillance Unit (BPSU) from April 2013 to April 2014.Setting A monthly surveillance of >3700 consultant paediatricians and paediatric surgeons in the UK and Ireland using the BPSU.Patients Children aged 0–14 years with a new diagnosis of AP.Main outcome measures The outcomes following AP, including the incidence of complications and comorbidity at diagnosis and at 1 year.Results Of the 94 new confirmed cases of AP identified in the UK during the study period, 90 cases (96%) were included in the 1-year follow-up. 30 patients (32%) developed further episode(s) of AP. Over one-fifth of patients developed one or more major complication. At initial admission, the most common of these was pancreatic necrosis (n=8, 9%), followed by respiratory failure (n=7, 7%). Reported complications by 1 year were pseudocyst formation (n=9, 10%), diabetes requiring insulin therapy (n=4, 4%) and maldigestion (n=1, 1%). At 1-year postdiagnosis, only 59% of children made a full recovery with no acute or chronic complications or recurrent episodes of AP. Two patients died, indicating a case fatality of ~2.0%.Conclusions AP in childhood is associated with significant short-term and medium-term complications and comorbidities including risk of recurrence in approximately a third of cases.Data may be obtained from a third party and are not publicly available.