Table 3

Vital signs and central haemodynamic parameters

ParameterTime 1Time 2Time 3P value
HR (/min)*138.5 (17.5)118.5 (15.6)120.8 (15.1)<0.01
Systolic BP (mm Hg)*70.5 (10.3)66.6 (11.7)75.8 (11.3)0.08
Diastolic BP (mm Hg)*42.5 (12.4)44.4 (11.5)50.9 (12.6)0.21
BP mean (mm Hg)*52.1 (10.5)52.7 (11.2)59.2 (11.6)0.20
LVO (mL/kg/min)*159.0 (42.0)141.1 (36.7)133.2 (43.3)0.05
AoMax (cm/s)*0.82 (0.14)0.80 (0.14)0.76 (0.13)0.15
RVO (mL/kg/min)*244.5 (76.3)211.1 (60.6)223.6 (63.9)0.01
PAMax (cm/s)*0.78 (0.17)0.70 (0.14)0.74 (0.14)0.11
PDA present20 (95.2)20 (95.2)7 (36.8)<0.01
TR present5 (23.8)3 (14.3)3 (16.7)0.60
  • *For continuous variables, mean (SD) and mixed model analysis of variance.

  • For categorical variables, frequency (%) and repeated measures logistic regression.

  • AoMax, aortic maximum flow; BP, blood pressure; HR, heart rate); LVO, left ventricular output; PAmax, pulmonary artery maximum flow; PDA, patent ductus arteriosus); RVO, right ventricular output; TR, tricuspid regurgitation.