Comparison of total and component scores of parent-reported HRQOL: controls versus CHD subjects
| Scale | Controls | CHD | Adjusted median | |||
| N | Median (IQR) | N | Median (IQR) | Difference (99% CI) | P values | |
| 2–4 years | ||||||
| Total scale score | 132 | 94.2 (90.3–97.4) | 147 | 86.1 (67.9–93.1) | −7.8 (−11.1 to −4.6) | <0.001 |
| Physical health summary | 132 | 100.0 (100.0–100.0) | 146 | 87.5 (65.6–100.0) | −12.5 (−12.5 to −12.5) | <0.001 |
| Psychosocial health summary | 132 | 90.9 (85.0–95.8) | 147 | 82.7 (72.5–94.2) | −7.7 (−12.6 to −2.8) | <0.001 |
| Emotional functioning | 132 | 80.0 (70.0–90.0) | 147 | 80.0 (60.0–90.0) | 0.0 (−9.3 to 9.3) | 1.000 |
| Social functioning | 132 | 100.0 (100.0–100.0) | 147 | 100.0 (85.0–100.0) | 0.0 (0.0 to 0.0) | 1.000 |
| School functioning | 97 | 100.0 (83.3–100.0) | 57 | 58.3 (33.3–100.0) | −41.7 (−51.6 to −31.8) | <0.001 |
| 5–7 years | ||||||
| Total scale score | 121 | 92.4 (88.0–95.7) | 67 | 77.2 (60.9–85.9) | −16.2 (−22.3 to −10.0) | <0.001 |
| Physical health summary | 121 | 100.0 (93.8–100.0) | 67 | 71.9 (50.0–90.6) | −28.1 (−32.4 to −23.8) | <0.001 |
| Psychosocial health summary | 121 | 90.0 (85.0–93.3) | 67 | 80.0 (66.7–86.7) | −10.0 (−16.0 to −4.0) | <0.001 |
| Emotional functioning | 121 | 80.0 (70.0–90.0) | 67 | 70.0 (60–85.0) | −10.0 (−19.3 to 0.7) | 0.006 |
| Social functioning | 121 | 100.0 (100.0–100.0) | 66 | 90.0 (75.0–100.0) | −10.0 (−10.2 to −9.8) | <0.001 |
| School functioning | 121 | 90.0 (85.0–100.0) | 64 | 80.0 (70.0–90.0) | −12.5 (−18.5 to −6.5) | <0.001 |
| 8–12 years | ||||||
| Total scale score | 245 | 91.3 (87.0–95.7) | 50 | 75.0 (58.4–85.3) | −17.4 (−24.8 to −10.0) | <0.001 |
| Physical health summary | 245 | 100.0 (93.8–100.0) | 49 | 67.9 (45.3–85.9) | −31.3 (−35.2 to −27.3) | <0.001 |
| Psychosocial health summary | 245 | 90.0 (83.3–94.2) | 49 | 78.3 (63.3–89.2) | −11.7 (−19.3 to −4.1) | <0.001 |
| Emotional functioning | 245 | 80.0 (70.0–90.0) | 50 | 75.0 (58.8–90.0) | −5.0 (−16.1 to 6.1) | 0.244 |
| Social functioning | 245 | 100.0 (100.0–100.0) | 50 | 90.0 (75.0–100.0) | −10.0 (−10.0 to −10.01) | <0.001 |
| School functioning | 245 | 90.0 (80.0–100.0) | 50 | 75.0 (53.8–90.0) | −15.0 (−23.7 to −6.3) | <0.001 |
| 13–18 years | ||||||
| Total scale score | 221 | 92.4 (85.9–95.7) | 42 | 70.7 (61.6–85.9) | −21.6 (−28.6 to −14.7) | <0.001 |
| Physical health summary | 221 | 96.9 (90.6–100.0) | 39 | 59.4 (40.6–87.5) | −37.5 (−47.1 to −27.9) | <0.001 |
| Psychosocial health summary | 221 | 90.0 (83.3–94.2) | 39 | 78.3 (68.3–95.0) | −11.7 (−20.5 to −2.9) | 0.001 |
| Emotional functioning | 221 | 80.0 (70.0–90.0) | 42 | 70.0 (53.8–90.0) | −15.0 (−33.0 to 3.0) | 0.032 |
| Social functioning | 221 | 100.0 (100.0–100.0) | 42 | 95.0 (85.0–100.0) | −5.0 (−5.0 to −5.0) | <0.001 |
| School functioning | 221 | 90.0 (80.0–100.0) | 40 | 75.0 (50.0–93.8) | −15.0 (−28.7 to −1.3) | 0.005 |
| Total | ||||||
| Total scale score | 719 | 92.4 (87.0–95.7) | 306 | 78.3 (63.0–90.5) | −14.1 (−16.7 to −11.6) | <0.001 |
| Physical health summary | 719 | 100.0 (93.8–100.0) | 301 | 81.3 (56.3–96.9) | −18.8 (−20.5 to −17.0) | <0.001 |
| Psychosocial health summary | 719 | 90.0 (83.3–95.0) | 302 | 81.7 (68.3–91.9) | −8.9 (−11.6 to −6.1) | <0.001 |
| Emotional functioning | 719 | 80.0 (70.0–90.0) | 306 | 75.0 (60.0–90.0) | −7.3 (−12.6 to −1.9) | <0.001 |
| Social functioning | 719 | 100.0 (100.0–100.0) | 305 | 100.0 (80.0–100.0) | 0.0 (0.0 to 0.0) | 1.000 |
| School functioning | 684 | 90.0 (80.0–100.0) | 211 | 75.0 (50.0–90.0) | −20.0 (−25.8 to −14.2) | <0.001 |
CHD, congenital heart disease; HRQOL, health-related quality of life.