Scale | Functional class categories† | |||
Acyanotic CHD | Cyanotic CHD | P values | ||
DPB (1) | IPB (2) | SVP (3) | ||
AMD (99% CI) | AMD (99% CI) | AMD (99% CI) | ||
Cardiac scales child report | ||||
Heart problems | −17.9 (−33.4 to −2.3) | −14.3 (−49.6 to 21.0) | −17.3 (−34.2 to −0.4) | (1) 0.003, (2) 0.293, (3) 0.009 |
Treatment | 0.0 (−11.9 to 11.9) | −15.0 (−54.2 to 24.2) | 2.5 (−8.5 to13.5) | (1) 1.000, (2) 0.315, (3) 0.550 |
Physical appearance | −4.2 (−17.5 to −9.2) | −20.8 (−47.8 to 6.2) | −4.2 (−14.9 to 6.5) | (1) 0.418, (2) 0.046, (3) 0.311 |
Anxiety | 0.0 (−18.1 to 18.1) | −6.3 (−38.6 to 26.1) | −6.3 (−27.2 to 14.7) | (1) 1.000, (2) 0.615, (3) 0.437 |
Cognitive problems | −16.7 (−28.4 to −4.9) | 0.0 (−16.5 to 16.5) | −16.7 (−27.4 to −5.9) | (1)<0.001, (2) 1.000, (3)<0.001 |
Communication | −2.8 (−19.0 to 13.5) | 2.8 (−18.8 to 24.4) | 2.8 (−12.2 to 17.8) | (1) 0.657, (2) 0.737, (3) 0.629 |
Cardiac scales parent report | ||||
Heart problems | −21.4 (−32.6 to −10.2) | −3.5 (−34.7 to 27.5) | −21.4 (−33.4 to −9.4) | (1)<0.001, (2) 0.766, (3)<0.001 |
Treatment | −4.3 (−22.0 to 13.3) | −7.7 (−39.9 to 24.6) | 0.7 (−12.4 to 13.7) | (1) 0.523, (2) 0.536, (3) 0.894 |
Physical appearance | 0.0 (−1.9 to 1.9) | 0.0 (−10.8 to 10.8) | 0.0 (−3.3 to 3.3) | (1) 1.000, (2) 1.000, (3) 1.000 |
Anxiety | −12.5 (−26.5 to 1.5) | −12.5 (−48.1 to 23.1) | 0.0 (−19.0 to 19.0) | (1) 0.022, (2) 0.363, (3) 1.000 |
Cognitive problems | 0.0 (−3.8 to 3.8) | 0.0 (−17.7 to 17.7) | −8.3 (−15.6 to −1.1) | (1) 1.000, (2) 1.000, (3) 0.003 |
Communication | −10.0 (−27.4 to 7.4) | −10.0 (−36.9 to 16.9) | −16.7 (−34.5 to 1.2) | (1) 0.138, (2) 0.334, (3) 0.016 |
*With left to right shunts (LRS) as reference.
†Functional class LSOL (left-sided obstructive lesions) was excluded from the subgroup analysis as the numbers were less in this group.
AMD, adjusted median difference; CHD, congenital heart disease; DPB, decreased pulmonary blood flow; IPB, increased pulmonary blood flow; SVP, single ventricle physiology.