Table 2

Clinical characteristics of children with suspected hypersensitivity reactions to beta-lactam antibiotics

Number of reactions
N=232
Age at reaction
Mean±SD (years)6.66±3.06
Median (range)3 (1–14)
Type of reaction
 Delayed154 (67.2%)
 Not determined51 (22%)
 Immediate24 (10.5%)
Symptoms
 Exanthema121 (52.2%)
 Urticaria78 (33.6%)
 Angioedema31 (13.4%)
 Serum sickness like15 (6.5%)
Antibiotics
 Amoxicillin/clavulanate147 (63.4%)
 Amoxicillin45 (19.4%)
 Cefuroxime16 (6.9%)
 Cefaclor11 (4.7%)
 Cefixime6 (2.6%)
 Penicilin V3 (1.3%)
 Cefotaxime1 (0.4%)