Table 1

Baseline characteristics of both groups showing a balanced sample without significant differences between the groups

Baseline characteristicsGroup with hypotonic solution
n=151
Group with isotonic solution
n=143
P value
Age in months*21, 3–10918, 2–1100.13†
Age in months*
 <12
 12–24
 >24
21, 3–109
56
53
45
18, 2–110
67
40
38
0.13†
Sex
 Male
73590.22‡
Time at study enrolment*6±3.25±2.60.43†
Serum sodium concentrations on admission ​​(mEq/L)142 (141–145)143 (139–146)0.75†
Potassium values ​​(mEq/L)4 (3.4–4.4)3.9 (3.5–4.8)0.71†
Glucose values ​​in blood (mg/dL)121 (109–171)134 (110–168)0.69†
Blood pH on admission7.41 (7.35–7.45)7.402 (7.39–7.51)0.67†
Total volume infused by weight (mL/kg/day)69 (45.2–90.3)105 (35.8–112.8)0.62†
DiagnosisTotal
N=294
Group with hypotonic solution
n=151
Group with isotonic solution
n=143
P value
Asthma13670.11‡
Acute respiratory infectious disease10953560.72‡
Postbone marrow transplant2314110.66‡
Postsurgical
 Neurosurgical2110110.78‡
 Thoracic2511140.26‡
 Abdominal3419120.77‡
Oncological chemotherapy plan3723130.54‡
Seizure disorder3215190.86‡
  • *Median, IQR (25–75).

  • †Wilcoxon test.

  • ‡Pearson’s χ2 test.