Relationship between MRI findings and neurodevelopmental impairment
| No or mild impairment n=52 (n, %) | Moderate to severe impairment n=12 (n, %) | P value | |
| Severity of injury according to NICHD scoring | 0.001 | ||
| 0 or 1A or 1B | 45 (86.5) | 5 (41.7) | |
| ≥2A | 7 (13.5) | 7 (58.3) | |
| Barkovich scoring system | |||
| Basal ganglia | <0.001 | ||
| 0, 1 | 51 (98.1) | 6 (50) | |
| 2, 3, 4 | 1 (1.9) | 6 (50) | |
| Watershed | 0.006 | ||
| 0, 1, 2 | 47 (90.4) | 7 (58.3) | |
| 3, 4, 5 | 5 (9.6) | 5 (41.6) | |
| Predominant pattern of injury | 0.06 | ||
| Normal | 33 (63.5) | 3 (25) | |
| Focal-multifocal | 7 (13.5) | 2 (16.6) | |
| Watershed | 9 (17.3) | 4 (33.3) | |
| BG/T | 3 (5.7) | 2 (16.6) | |
| Total brain injury | 0 | 1 (8.3) | |
| Moderate to severe brain injury* | 5 (9.6) | 6 (50) | 0.001 |
*Moderate to severe brain injury defined as WS score of ≥3 or BG/T score ≥2.
†Moderate to severe impairment was defined as confirmed cerebral palsy, deafness, blindness or severe visual impairment and global developmental delay.
BG/T, Basal Ganglia/Thalamus; NICHD, National Institute of Child Health and Human Development; WS, Watershed.