Table 2

Summary of the available information of all the cases of congenital cytomegalovirus infection reported (maternal information, symptoms and neuroimaging findings at birth and on follow-up)

Maternal infectionAt birth6 months1 year2 years3 years4 years
1PrimaryAAAAA
2RecurrentAAAAA
3PrimaryAAAA
4PrimaryAAAA
5UnknownA
6UnknownAA
7RecurrentAAAAA
8UnknownIUGR, HA
9PrimaryIUGR, VACP, DCD, M, S
10UnknownAn, Cr, H, Hs, J, L, SBB, S, TAA
11RecurrentAn, Ch, H, T, HsCH, VSVAHAt, DDS, DDFM, AMRI
12UnknownAn, J, L, T
13UnknownA
14RecurrentJ
15PrimaryAMRI
16PrimaryA
17PrimaryA
18PrimaryA
19PrimaryAn, N, Vm
20RecurrentAn, H, Hs, IC, SL, T
21PrimaryA
22PrimaryA
23UnknownA
24PrimaryA
25PrimaryA
26PrimaryA
27RecurrentAn, Sp
28PrimaryA
29PrimaryIUGR
30RecurrentA
31RecurrentVSV
32PrimaryIC
33RecurrentIUGR, PCL
34RecurrentSL, L, T
35RecurrentSL, L, T, IUGR
36RecurrentIUGR
37PrimaryAn, T, IC, D
38PrimaryA
39PrimaryA
40PrimaryA
  • A, asymptomatic; AH, axial hypotonia; AMRI, abnormal MRI (unspecified); An, anaemia; At, ataxia; CH, cerebellar hypoplasia; CP, cerebral palsy; Ch, cholestasis; Cr, chorioretinitis; D, dystonia; DCD, diffuse cortical dysplasia; DDFM, delayed development of fine movements; DS, delayed speech; H, hepatitis; Hs, hepatosplenomegaly; IC, intracerebral calcifications; IUGR, intrauterine growth restriction; J, jaundice; L, leucopaenia; M, microcephaly; N, neutropaenia; PCL, periventricular cystic lesions; S, strabismus; SBB, subependymal bilateral bleeding; SL, sepsis-like; Sp, splenomegaly; T, thrombocytopaenia; VA, ventricular asymmetry; VSV, ventriculostriated vasculopathy; Vm, ventriculomegaly.