Table 1

Characteristics of patients included in the primary analysis

Pneumonia
(n=30)
Other SBIs
(n=66)
Viral
(n=495)
Predictor variables
Age (months)24.5 (12.7–41.3)15.0 (8.0–33.0)15.0 (7.0–28.0)
Gender, male 19 (63%)32 (49%)280 (57%)
Duration of fever (days)3 (2–5)2 (1–4)2 (1–4)
Temperature (°C)38.6 (38.2–39.8)38.7 (37.8–39.4)38.5 (37.6–39.2)
n=30 (100%)n=66 (100%)n=493 (99%)
Respiratory rate 50 (34–70)40 (31–52)38 (30–52)
n=15 (50%)n=31 (47%)n=252 (51%)
Tachypnoea 12 (80%)17 (55%)130 (52%)
Heart rate 160 (24)152 (27)151 (24)
n=29 (97%)n=57 (86%)n=453 (92%)
Tachycardia 21 (72%)29 (51%)232 (51%)
Oxygen saturation (%O2 )98 (97–99)99 (97–100)98 (96–100)
n=28 (93%)n=48 (73%)n=417 (84%)
Desaturation (<94%O2 )1 (4%)0 (0%)24 (6%)
Chest wall retractions 6 (20%)4 (6%)60 (12%)
n=30 (100%)n=63 (95%)n=484 (98%)
Ill appearance 13 (43%)25 (38%)141 (29%)
C reactive protein (mg/l)176 (72–224)102 (55–151)15 (5–36)
Assay score 98 (76–100)88 (68–98)4 (1–26)
Other variables
Hospital admission 22 (73%)51 (77%)255 (52%)
Hospitalisation duration (days)4 (3–6)4 (3–5)3 (2–4)
Antibiotic treatment prescribed 30 (100%)63 (96%)140 (29%)
Recruiting site
Secondary care centre27 (90%)63 (96%)463 (94%)
Tertiary care centre3 (10%)3 (4%)32 (6%)
Focus of infection
Central nervous system0 (0%)0 (0%)9 (2%)
Gastrointestinal tract0 (0%)1 (2%)19 (4%)
Other3 (10%)11 (17%)39 (8%)
Respiratory tract26 (87%)18 (27%)250 (50%)
Systemic0 (0%)2 (3%)9 (2%)
Unknown1 (3%)10 (15%)169 (34%)
Urinary tract0 (0%)24 (36%)0 (0%)
  • Data are presented as n (%), median (IQR) or mean (SD). This table includes imputed reference standard diagnoses, data are based on 1 of the 10 imputed data sets. If data were not available for all patients, the total number of available data are noted. Clinical syndrome was based on the diagnosis of the attending physician at discharge from the hospital. LRTI included pneumonia and bronchiolitis; URTI included laryngitis, pharyngitis, otitis media, sinusitis and tonsillitis. LRTI: lower respiratory tract infection; URTI: upper respiratory tract infection

  • SBI, serious bacterial infection.