Morphine
| Morphine | n | Study type | Absorption | VD (L/kg) | Metabolite CL (mL/kg/hour) | CL (mL/kg/hour) | t1/2 (hour) |
| Favié et al45 | 244 | Prospective | / | 2.54 | M3G=0.130 M6G=0.494 ↓14.7%=↓4.91%/ºC | 259.0 ↓20.7%=↓6.89%/ºC | / |
| Róka et al44 | 16 | Observational | / | / | / | ‘could not be calculated’ | / |
| Frymoyer et al23 | 20 | Prospective | / | 2.286 ↓37.0%=↓12.3%/ºC | M3G=0.188 M6G=0.197 | 216.0 ↓46.7%=↓15.6%/ºC | / |