Table 3

Univariate and multivariate analysis (with and without CRP) of clinical and laboratory predictors of infants with serious bacterial infections

Univariate analysisMultivariate analysis without CRPMultivariate analysis with CRP
Unadjusted OR (95% CI)P valueAdjusted OR (95% CI)P valueAdjusted OR (95% CI)P value
Age at presentation1.016 (1.004 to 1.028)0.0081.012 (0.998 to 1.026)0.0991.006 (0.991 to 1.021)0.424
Gender3.968 (1.885 to 8.354)0.0054.049 (1.740 to 9.424)0.0013.935 (1.597 to 9.693)0.003
<24 hour of fever at presentation0.325 (0.148 to 0.711)0.0050.418 (0.165 to 1.062)0.0670.978 (0.318 to 3.008)0.969
WBC1.108 (1.038 to 1.177)0.0010.730 (0.540 to 0.986)0.0400.762 (0.559 to 1.039)0.086
ANC1.224 (1.100 to 1.347)<0.0012.318 (1.245 to 4.315)0.0081.934 (1.007 to 3.714)0.048
NLR1.631 (1.141 to 2.330)0.0070.279 (0.077 to 1.018)0.0530.330 (0.085 to 1.282)0.109
CRP1.053 (1.030 to 1.074)<0.0011.037 (1.013 to 1.063)0.003
  • ANC, absolute neutrophil ratio; CRP, C-reactive protein; NLR, neutrophil to lymphocyte ratio; WBC, white blood cell count.