Table 4

Significant univariate associations between infant mortality and infant-related factors of VLBW infants

Variables CategoryRisk Ratio (95% CI)P value
GenderFemale vs Male1.02 (0.70 to 1.48)0.94
GA (weeks)25–32 vs 33–374.15 (2.93 to 5.88)<0.01
HIV exposedNo vs yes1.25 (1.00 to 1.56)0.05
Birth weight (g)≤1000 vs>10002.87 (2.08 to 3.96)<0.01
IUGRYes vs no0.47 (0.35 to 0.65)<0.01
Resuscitation at birthYes vs no4.45 (3.43 to 5.78)<0.01
Apgar 1 min0–6 vs 7–102.46 (1.99 to 3.05)<0.01
Apgar 5 min0–6 vs 7–102.42 (2.12 to 2.77)<0.01
HMDYes vs no2.03 (1.72 to 2.38)<0.01
Other illnessesYes vs no1.59 (1.20 to 2.09)0.01
Oxygen supportYes vs no9.68 (7.39 to 12.68)<0.01
Days on oxygen0–1 day vs >1 day1.44 (0.94 to 2.21)0.09
Surfactant givenYes vs no3.59 (2.77 to 4.65)<0.01
Weight gainYes vs no3.39 (2.21 to 5.19)<0.01
SepsisYes vs no6.41 (3.78 to 10.88)<0.01
Intracranial haemorrhage (ICH)Yes vs no5.19 (3.03 to 8.90)<0.01
Persistant ductus arteriosus PDANo vs yes2.83 (1.47 to 5.47)<0.01
Resuscitation during stayYes vs no12.31 (5.85 to 25.88)0.01
  • Infant-related factors that were not significantly associated with mortality in the univariate regression analysis are not shown in this table, besides gender.

  • ANC, antenatal clinic; GA, gestational age; HMD, hyaline membrane disease; ICH, intracranial haemorrhage; IUGR, intrauterine growth restriction; Other, other problems like neonatal jaundice, hypoglycaemia, necrotising enterocolitis, hypothermia; PDA, persistent ductus arteriosus; VLBW, very low birth weight.