Table 2

Neurodevelopmental outcomes at 24 months

	No episodes of hypoglycaemia	At least one episode of hypoglycaemia (<2.6 mmol/L)	p Value*	Two or more episodes of hypoglycaemia (<2.6 mmol/L)	p Value*	Three or more episodes of hypoglycaemia (<2.6 mmol/L)	p Value*
*BSID-III scores (mean, SD)*
Cognitive subscale	99 (19)	98 (18)	0.813	96 (21)	0.499	83 (25)	0.030
Language subscale	93 (20)	92 (21)	0.875	87 (23)	0.349	71 (26)	0.020
Socioemotional subscale	99 (20)	99 (22)	0.915	93 (25)	0.640	74 (23)	0.004
Motor subscale	97 (18)	97 (18)	0.976	94 (22)	0.316	86 (30)	0.385
Adverse outcomes in survivors (n, %)
BSID cognitive or language<70	7/70 (10)	4/34 (12)	0.747	3/20 (15)	0.686	3/9 (33)	0.082
Blindness	0 (0)	1/34 (3)	0.327	1/20 (5)	0.222	1/9 (11)	0.114
Deafness	1/70 (1)	3/34 (9)	0.101	3/20 (15)	0.033	2/9 (22)	0.033
Cerebral palsy	5/70 (7)	4/34 (12)	0.470	3/20 (15)	0.369	2/9 (22)	0.179
Any disability	8/70 (11)	7/34 (21)	0.242	6/20 (30)	0.074	5/9 (55)	0.005
Composite outcome (n, %)
Death	14/84 (17)	4/38 (11)	0.425	2/22 (9)	0.515	2/11 (18)	1.0
Death or disability	22/84 (26)	11/38 (29)	0.827	8/22 (36)	0.426	7/11 (64)	0.031