Covariates | Category | Outcome status | P>|z| | Crude HR (95% CI) | P>|z| | Adjusted HR (95% CI) | |
Attrited | Censored | ||||||
Child age | 92 | 162 | 0.205 | 0.96 (0.90 to 1.02) | 0.131 | 0.82 (0.63 to 1.06) | |
Residence | Rural | 50 | 71 | 0.088 | 1.43 (0.95 to 2.16) | 0.348 | 1.50 (0.64 to 3.47) |
Urban | 42 | 91 | — | — | — | — | |
Caregiver’s marital status | Single | 10 | 14 | 0.204 | 1.55 (0.80 to 3.03) | 0.730 | 1.29 (0.31 to 5.38) |
Married | 58 | 113 | 0.287 | 1.49 (0.71 to 3.13) | 0.399 | 1.71 (0.49 to 5.99) | |
Divorced | 8 | 11 | 0.569 | 1.17 (0.67 to 2.05) | 0.380 | 1.62 (0.55 to 4.75) | |
Widowed | 16 | 24 | — | — | — | — | |
Developmental status (for <5 years) | Appropriate | 32 | 57 | — | — | — | — |
Delayed | 10 | 3 | 0.002 | 3.15 (1.53 to 6.49) | 0.021* | 3.60 (1.22 to 10.66) | |
WFA | Normal | 72 | 152 | — | — | — | — |
Underweight | 20 | 10 | <0.001 | 3.28 (1.98 to 5.45) | 0.007* | 5.91 (1.61 to 21.71) | |
HFA | Normal | 75 | 154 | — | — | — | — |
Stunted | 17 | 8 | <0.001 | 2.88 (1.69 to 4.89) | 0.215 | 0.39 (0.09 to 1.74) | |
Baseline haemoglobin | <10 mg/dL | 51 | 23 | <0.001 | 3.87 (2.56 to 5.85) | 0.005* | 3.12 (1.41 to 6.93) |
≥10 mg/dL | 41 | 139 | — | — | — | — | |
Baseline CD4+ count | ≤200 | 23 | 12 | <0.001 | 2.53 (1.57 to 4.06) | 0.004* | 4.43 (1.62 to 12.18) |
>200 | 69 | 150 | — | — | — | — | |
WHO stage | Early | 53 | 121 | — | — | — | — |
Advanced | 39 | 41 | 0.015 | 1.67 (1.11 to 2.53) | 0.068 | 2.29 (0.94 to 5.59) | |
OIs | No | 66 | 133 | — | — | — | — |
Yes | 26 | 29 | 0.161 | 1.38 (0.88 to 2.18) | 0.395 | 1.44 (0.62 to 3.40) | |
Presence of TB | No | 82 | 151 | — | — | — | — |
Yes | 10 | 11 | 0.148 | 1.63 (0.84 to 3.15) | 0.240 | 0.51 (0.17 to 1.57) | |
Adherence | Good | 45 | 150 | — | — | — | — |
Suboptimal | 47 | 2 | <0.001 | 5.55 (3.65 to 8.46) | 0.004* | 3.45 (1.50 to 7.94) | |
CPT | Given | 75 | 147 | — | — | — | — |
Not given | 17 | 15 | 0.019 | 1.88 (1.11 to 3.18) | 0.290 | 1.81 (0.60 to 5.40) | |
ARV drug side effect | Yes | 44 | 34 | 0.009 | 1.73 (1.15 to 2.61) | 0.125 | 0.51 (0.21 to 1.21) |
No | 48 | 128 | — | — | — | — | |
ARV drug substitution | Yes | 22 | 52 | — | — | — | — |
No | 70 | 110 | 0.007 | 1.96 (1.20 to 3.19) | 0.153 | 1.90 (0.79 to 4.61) |
*Significant at 5% level of significance.
ARV, antiretroviral drugs; CPT, cotrimoxazole preventive therapy; HFA, height-for-age; OIs, opportunistic infections; TB, tuberculosis; WFA, weight-for-age.