Logistic regression analysis of potential predictors of in-hospital mortality in the two epochs
| Potential predictors | Epoch-1 (2009–2013) | Epoch-2 (2014–2018) | ||
| OR (95% CI) | Adjusted OR (95% CI) | OR (95% CI) | Adjusted OR (95% CI) | |
| Birth weight, g | ||||
| ≥1500 g | 1 | 1 | 1 | 1 |
| <750 | 55.01 (44.88 to 67.44) | 28.95 (22.20 to 37.74) | 58.35 (47.16 to 72.21) | 29.79 (23.14 to 38.35) |
| 750–999 | 9.43 (7.85 to 11.34) | 5.99 (4.69 to 7.65) | 10.26 (8.40 to 12.54) | 6.24 (4.90 to 7.94) |
| 1000–1249 | 3.28 (2.71 to 3.97) | 2.63 (2.05 to 3.38) | 3.19 (2.59 to 3.94) | 2.52 (1.97 to 3.22) |
| 1250–1499 | 1.62 (1.31 to 2.00) | 1.66 (1.27 to 2.16) | 1.44 (1.14 to 1.82) | 1.29 (0.98 to 1.69) |
| Admission temperature | ||||
| ≥36.5°C | 1 | 1 | 1 | 1 |
| 36.0°C–36.4°C | 1.29 (1.16 to 1.45) | 1.10 (0.94 to 1.29) | 1.30 (1.14 to 1.49) | 1.09 (0.92 to 1.30) |
| 32.0°C–35.9°C | 2.08 (1.89 to 2.30) | 1.31 (1.13 to 1.50) | 2.58 (2.31 to 2.87) | 1.44 (1.24 to 1.67) |
| <32.0°C | 13.76 (7.53 to 25.14) | 2.19 (0.77 to 6.20) | 13.54 (8.60 to 21.33) | 3.80 (1.84 to 7.88) |
| No antenatal steroids | 2.12 (1.95 to 2.31) | 1.94 (1.70 to 2.22) | 2.44 (2.22 to 2.68) | 1.70 (1.48 to 1.96) |
| Outborns | 1.09 (0.97 to 1.23) | 1.09 (0.90 to 1.31) | 1.28 (1.12 to 1.46) | 0.89 (0.72 to 1.10) |
| Modes of delivery | ||||
| LSCS | 1 | 1 | 1 | 1 |
| Vertex | 1.72 (1.58 to 1.87) | 1.13 (0.995 to 1.28) | 2.013 (1.84 to 2.20) | 1.54 (1.36 to 1.75) |
| Breech | 3.79 (3.19 to 4.50) | 2.08 (1.62 to 2.67) | 3.99 (3.31 to 4.82) | 2.12 (1.63 to 2.76) |
| No surfactant therapy | 0.99 (0.90 to 1.08) | 1.04 (0.90 to 1.20) | 0.99 (0.91 to 1.09) | 1.20 (1.05 to 1.37) |
| No eCPAP therapy | * | * | 3.04 (2.77 to 3.33) | 1.67 (1.48 to 1.89) |
| Admitted to : | ||||
| Large NICU | 1 | 1 | 1 | 1 |
| Intermediate-sized NICU | 1.14 (1.05 to 1.24) | 1.18 (1.04 to 1.34) | 1.14 (1.04 to 1.24) | 1.22 (1.07 to 1.38) |
| Small NICU | 1.14 (1.00 to 1.29) | 1.30 (1.09 to 1.56) | 1.17 (1.03 to 1.33) | 1.38 (1.15 to 1.65) |
| LOS | 1.65 (1.47 to 1.84) | 1.35 (1.17 to 1.57) | 2.45 (1.97 to 2.57) | 1.52 (1.27 to 1.81) |
| Pneumothorax | 5.41 (4.53 to 6.47) | 6.34 (4.90 to 8.20) | 4.90 (3.97 to 6.03) | 5.55 (4.20 to 7.34) |
| NEC | 1.86 (1.61 to 2.14) | 1.72 (1.42 to 2.09) | 2.12 (1.79 to 2.51) | 2.04 (1.65 to 2.54) |
| sIVH | 9.20 (8.20 to 10.33) | 6.15 (5.33 to 7.10) | 9.87 (8.70 to 11.18) | 6.64 (5.69 to 7.76) |
*Not included in analysis because no data were collected in 2009 and 2010.
eCPAP, early continuous positive airway pressure; LOS, late-onset sepsis; LSCS, lower segment caesarean section; MCV, mechanical conventional ventilation; MCV, mechanical conventional ventilation; NEC, necrotising enterocolitis; NICU, neonatal intensive care unit; sIVH, severe intraventricular haemorrahge; TPN, total parenteral nutrition.