Factors | All anomalies | Isolated anomalies | Multiple anomalies | Cardiovascular anomalies |
Ethnicity: other vs white | 2.25 (1.77–2.86) | 1.87 (1.16–3.02) | 2.38 (1.79–3.16) | 1.08 (0.29–4.04) |
Parity ≥1 vs nulliparous | 1.24 (1.08–1.41) | 1.48 (1.16–1.89) | 1.19 (1.02–1.40) | |
Maternal smoking: smoker vs non-smoker/ex-smoker | 1.20 (1.02–1.40) | 1.44 (1.07–1.92) | ||
Infant sex: female vs male | 1.28 (1.13–1.46) | 1.06 (0.85–1.33) | 1.37 (1.17–1.61) | 1.26 (0.78–2.06) |
Gestational age at birth: preterm vs term | 4.38 (3.86–4.98) | 4.53 (3.62–5.67) | 3.86 (3.30–4.53) | 3.67 (2.19–6.16) |
CHD severity: moderate vs less Most vs less | n/a | n/a | n/a | 18.4 (8.10–41.7) 229 (90.8–579) |
Surgery: yes vs no | 0.80 (0.68–0.95) | 0.71 (0.58–0.86) | 0.34 (0.15–0.75) |
Statistical significance at p<0.05. aORs with 95% CIs are given. Empty cells represent variable that was not included in the multivariable analysis.
aORs, adjusted ORs ; CHD, congenital heart defects; n/a, not applicable.