Unadjusted and adjusted factors associated with repeated (2+) and single (1) admissions of infants with cardiovascular anomalies
| 2+ admissions | 1 admission | |||
| Cardiovascular, n=997 | ||||
| Factors | Unadjusted OR† | Adjusted OR‡ | Unadjusted OR† | Adjusted OR‡ |
| Townsend quintile | ||||
| 1 | 1 (reference) | 1 (reference) | ||
| 2 | 1.11 (0.80 to 1.53) | 0.80 (0.56 to 1.12) | ||
| 3 | 1.35 (0.99 to 1.85) | 0.94 (0.68 to 1.31) | ||
| 4 | 1.10 (0.81 to 1.50) | 1.05 (0.77 to 1.43) | ||
| 5 | 1.40 (1.05 to 1.85) | 0.97 (0.72 to 1.30) | ||
| Maternal ethnicity | ||||
| White | 1 (reference) | 1 (reference) | ||
| Other | 0.82 (0.49 to 1.38) | 0.91 (0.53 to 1.57) | ||
| Maternal age at delivery, years | ||||
| ≤24 | 1.20 (0.95 to 1.53) | 0.94 (0.72 to 1.23) | ||
| 25–29 | 1 (reference) | 1 (reference) | ||
| 30–34 | 1.02 (0.80 to 1.31) | 1.08 (0.83 to 1.41) | ||
| ≥35 | 0.57 (0.43 to 0.75) | 0.67 (0.51 to 0.90) | ||
| Parity | ||||
| Nulliparous | 1 (reference) | 1 (reference) | ||
| ≥1 | 0.92 (0.76 to 1.11) | 0.86 (0.70 to 1.05) | ||
| Multiple fetus | ||||
| Yes | 1.86 (1.15 to 3.00) | 1.55 (0.91 to 2.62) | ||
| No | 1 (reference) | 1 (reference) | ||
| Maternal smoking | ||||
| Smoker | 1.39 (1.07 to 1.79) | 1.07 (0.81 to 1.42) | ||
| Non/ex-smoker | 1 (reference) | 1 (reference) | ||
| Anomalies in previous pregnancies | ||||
| Yes | 1.32 (0.94 to 1.86) | 1.20 (0.84 to 1.71) | ||
| No | 1 (reference) | 1 (reference) | ||
| Infant sex* | ||||
| Male | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) |
| Female | 0.66 (0.55 to 0.79) | 0.75 (0.62 to 0.91) | 0.95 (0.78 to 1.15) | 0.95 (0.78 to 1.15) |
| Gestational age,* week | ||||
| <37 | 3.33 (2.55 to 4.35) | 3.76 (2.86 to 4.93) | 1.97 (1.46 to 2.65) | 1.97 (1.46 to 2.66) |
| ≥37 | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) |
| CHD disease severity* | ||||
| Less severity | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) |
| Moderate severity | 5.83 (4.19 to 8.11) | 6.25 (4.47 to 8.74) | 1.14 (0.75 to 1.75) | 1.18 (0.77 to 1.81) |
| Most severe | 2.67 (1.57 to 4.57) | 2.72 (1.58 to 4.71) | 0.38 (0.15 to 0.94) | 0.39 (0.16 to 0.96) |
*Variable identified for inclusion a priori.
†Statistically significant at p<0.1 for unadjusted OR.
‡Adjusted variables include infant sex, gestational age and disease severity. Statistically significant at p<0.05.
CHD, congenital heart defect.