Table 4

Timing and duration of treatment for PDA among infants born at <32 weeks’ gestational age in England and Wales from 2010 to 2017

IndomethacinIbuprofenParacetamolSurgery
Infants who received treatment, n (%)1255 (7.6)4428 (26.9)3857 (23.5)916 (5.6)
No of days of use, median (IQR)3 (2–5)3 (2–4)3 (2–7)NA
Day after birth at first treatment, median (IQR)8 (4–15)10 (6–16)58 (21–73)33 (24–45)
PMA at first treatment (completed weeks), median (IQR)27 (25–28)27 (25–28)34 (29–37)29 (28–31)
  • PDA, patent ductus arteriosus; PMA, post-menstrual age.