Participants | Non-participants | P value | |
Background characteristics | |||
Male | 53 (46%) | 28 (49%) | 0.747 |
Multiparity | 28 (24%) | 20 (35%) | 0.152 |
Maternal education level | |||
Lower education level | 40 (35%) | 23 (40%) | 0.504 |
Higher education level | 75 (65%) | 34 (60%) | |
Clinical risk factors | |||
Birth weight, g | 806 (136) 447–995 | 796 (138) 520–995 | 0.673 |
Gestational age, weeks | 27.2 (1.9) 23.4–32.9 | 27.3 (2.0) 22.3–32.6 | 0.647 |
Gestational age <27 weeks | 60 (52%) | 28 (49%) | 0.747 |
Small for GA | 55 (48%) | 32 (56%) | 0.334 |
Antenatal steroid treatment | 93 (81%) | 47 (83%) | 0.839 |
Surfactant treatment | 71/113 (63%) | 37/57 (65%) | 0.867 |
Respiratory distress syndrome | 80/114 (70%) | 45/57 (79%) | 0.274 |
Sepsis | 32/114 (28%) | 16/57 (28%) | 1.00 |
IVH, grades 3–4 | 6/113 (5%) | 6/55 (11%) | 0.210 |
Retinopathy of prematurity, stages 3–4 | 11/115 (10%) | 4/56 (7%) | 0.776 |
Perforated necrotising enterocolitis | 7/114 (6%) | 3/57 (5%) | 1.00 |
Need for oxygen treatment at GA 36 weeks | 44/115 (38%) | 24/57 (42%) | 0.741 |
Outcome at 5 years | |||
Incidence of cerebral palsy at 5 years | 11/115 (10%) | 11/57 (19%) | 0.090 |
FSIQ at 5 years | 98.3 (21.3) 39–139 | 89.4 (19.0) 39–127 | 0.009 |
Data presented as mean (SD) and range, or as n (%).
ELBW, extremely low birthweight; FSIQ, Full-Scale Intelligence Quotient; GA, gestational age; IVH, intraventricular haemorrhage.