Adverse event n (%) | Ibuprofen group (n=179) | Oxycodone group (n=61) | Total (n=240) | P value* |
Any adverse event† | 98 (55.1) | 49 (81.7) | 147 (61.2) | <0.001 |
Drowsiness† | 70 (39.1) | 40 (66.7) | 110 (46.0) | <0.001 |
Lack of appetite† | 48 (26.8) | 22 (36.7) | 70 (29.3) | 0.15 |
Nausea | 19 (10.6) | 20 (33.3) | 39 (16.3) | <0.001 |
Dizziness | 14 (7.8) | 18 (30.0) | 32 (13.4) | <0.001 |
Constipation‡ | 10 (5.6) | 11 (18.3) | 21 (8.9) | 0.003 |
Abdominal pain | 10 (5.6) | 5 (8.3) | 15 (6.3) | 0.45 |
Vomiting | 3 (1.7) | 7 (11.7) | 10 (4.2) | <0.001 |
Rash | 3 (1.7) | 1 (1.7) | 4 (1.7) | 1.00 |
Other | 17 (9.5) | 5 (8.2) | 22 (9.2) | 0.76 |
Bold type represents statisitically significant results.
*Pearson’s χ2 test.
†n=238.
‡n=237.