Table 3

Mean intensity of adverse events

Adverse eventIbuprofen, mean (SD)Oxycodone, mean (SD)P value*
DrowsinessDay 1 (n=110)4.5 (2.1)5.1 (1.9)0.19
Cumulative (n=125)4.0 (2.0)4.4 (1.6)0.17
Lack of appetiteDay 1 (n=70)5.1 (2.1)4.4 (2.2)0.17
Cumulative (n=91)4.4 (2.0)3.8 (1.6)0.19
NauseaDay 1 (n=39)4.6 (2.7)5.9 (2.6)0.15
Cumulative (n=53)4.5 (2.6)5.2 (2.8)0.37
DizzinessDay 1 (n=32)4.8 (2.2)4.2 (1.8)0.43
Cumulative (n=42)4.2 (1.9)4.2 (1.7)0.94
ConstipationDay 1 (n=21)3.8 (1.9)4.5 (2.2)0.42
Cumulative (n=35)3.3 (2.2)4.9 (2.1)0.04
Abdominal painDay 1 (n=15)2.5 (1.4)5.4 (3.1)0.02
Cumulative (n=29)3.3 (2.3)3.6 (2.0)0.70
VomitingDay 1 (n=10)8.7 (1.2)7.3 (3.1)0.49
Cumulative (n=17)7.5 (3.3)5.7 (3.6)0.33
RashDay 1 (n=4)4.7 (2.1)4 (NA)†0.81
Cumulative (n=10)3.8 (2.3)4.3 (0.5)0.74
  • Bold type represents statisitically significant results.

  • *Two-sample t-test.

  • †SD is not applicable, as sample size is 1.