Cohort characteristics
| Nicol et al | Nkereuwem et al | Barrio et al | ||
| Cohort size | 241 | 415 | 79 | |
| Study design | Prospective enrolment Plus enrichment of CLHIV | Prospective enrolment | Prospective enrolment Plus control cohort | |
| Index test | Comparator | AlereLAM | AlereLAM | None |
| Sample storage | Yes, −80°C | Yes, −80°C | Yes, −20°C | |
| Country | South Africa | Gambia, Mali, Nigeria, Tanzania | Haiti | |
| Healthcare level of recruitment of study participants | Tertiary hospital | Mixed (community, tertiary hospital, urban comprehensive healthcare) | Reference hospital | |
| Age in months (median) Median (IQR) | 45.2 (21.2–88.8) | 67.2 (27.6–111.6) | 76 (58–121) | |
| Age categories | <5 years | 118 (58%) | 194 (47%) | 24 (30%) |
| ≥5 years | 86 (42%) | 221 (53%) | 55 (70%) | |
| Male sex | 111 (54%) | 225 (54%) | 51 (65%) | |
| TB status | Confirmed TB | 84 (41%) | 63 (15%) | 5 |
| Unconfirmed TB | 81 (40%) | 113 (27%) | 50 | |
| Unlikely TB | 39 (19%) | 239 (58%) | 24 | |
| HIV status | HIV infected | 40 (20%) | 61 (15%) | Excluded |
| CD4 cells/uL median (IQR) | 552 (206–849) | – | – | |
| Malnutrition | Stunted | 73 (40%) | 134 (32%) | 12 (21%) |
CLHIV, children living with HIV; LAM, lipoarabinomannan; TB, tuberculosis.