Multivariable linear regression* CBCL internalising behaviour predicted scores and score differences
| Puberty stages | Puberty stage differences | |||||
| Prepuberty | Early puberty | Late puberty | Pre to early | Early to late | Pre to late | |
| Males | ||||||
| TD | 47.2 (45.3, 49.1) | 47.4 (45.4, 49.3) | 47.4 (45.4, 49.5) | 0.1 (−1.5, 1.8) | 0.1 (−1.8, 2.0) | 0.2 (−1.6, 2.0) |
| ASD | 62.4 (61.1, 63.7) | 62.5 (61.1, 63.9) | 62.6 (61.1, 64.1) | |||
| ADHD | 61.0 (59.5, 62.4) | 61.1 (59.5, 62.7) | 61.2 (59.3, 63.0) | |||
| OCD | 63.3 (61.3, 65.2) | 63.4 (61.4, 65.4) | 63.5 (61.4, 65.6) | |||
| Females | ||||||
| TD | 44.5 (42.1, 46.9) | 47.7 (45.3, 50.1) | 48.9 (46.7, 51.2) | 3.2 (0.4, 6.0) P=0.025 | 1.2 (−1.4, 3.8) | 4.4 (1.7, 7.1) P=0.001 |
| ASD | 59.7 (57.5, 61.9) | 62.9 (60.8, 65.0) | 64.1 (62.2, 66.0) | |||
| ADHD | 58.2 (56.0, 60.5) | 61.5 (59.2, 63.7) | 62.7 (60.5, 64.8) | |||
| OCD | 60.6 (58.1, 63.1) | 63.8 (61.4, 66.1) | 65.0 (62.9, 67.1) | |||
| Males versus females | ||||||
| −3.1 (−6.3, 0.2) | −1.1 (−4.4, 2.1) | −4.2 (−7.4, −1.0) P=0.010 | ||||
Prepuberty: Tanner stage 1. Early puberty: Tanner stages 2–3. Late puberty: Tanner stages 4–5.
*Pubertal stage (F(2,1034)=4.1, p=0.02). Sex (F(1,1034)=0.2, p=0.7). Diagnosis (F(3,1034)=100.7, p<0.0001). Sex × pubertal stage (F(2,1034)=3.6, p=0.03).
ADHD, attention-deficit/hyperactivity disorder; ASD, autism spectrum disorder; CBCL, Child Behavior Checklist; OCD, obsessive-compulsive disorder; TD, typically developing.