Table 4

Discriminative value of VRI and PELOD-2 in predicting mortality in paediatric septic shock patients

Performance predictorVRI ≤32.1PELOD-2 ≥11
Sensitivity, % (95% CI)87.50 (71.01 to 96.49)34.40 (18.57 to 53.19)
Specificity, % (95% CI)88.90 (73.94 to 96.89)97.20 (85.47 to 99.93)
PPV, % (95% CI)87.50 (73.36 to 94.68)91.70 (60.03 to 98.77)
NPV, % (95% CI)88.89 (76.05 to 95.27)62.50 (56.32 to 68.30)
LR+, % (95% CI)7.25 (1.50 to 15.9)11.33 (1.00 to 12.00)
LR−, % (95% CI)0.14 (0.10 to 1.34)1.46 (0.30 to 5.36)
AUC % (95% CI)95 (90 to 100)92.6 (86.40 to 98.80)
P value<0.001<0.001
  • AUC, area under the curve; LR−, negative likelihood ratio; LR+, positive likelihood ratio; NPV, negative predictive value; PELOD-2, Paediatric Logistic Organ Dysfunction 2; PPV, positive predictive value; VRI, Vascular Reactivity Index.