Twins (n=2364) | Singletons (n=7167) | |||||
ACS exposed (n=2078) | ACS unexposed (n=286) | P value* | ACS exposed (n=6013) | ACS unexposed (n=1154) | P value* | |
Infant | ||||||
Gestational age (weeks), mean (SD) | 28.08 (2.19) | 27.75 (2.50) | 0.034 | 28.49 (2.52) | 28.39 (2.78) | 0.256 |
Birth weight (g), mean (SD) | 1059 (274) | 1034 (301) | 0.186 | 1060 (281) | 1073 (289) | 0.138 |
SGA, n (%) | 147 (7.1) | 22 (7.7) | 0.704 | 1080 (18.0) | 199 (17.2) | 0.560 |
Male, n (%) | 1079 (51.9) | 143 (50.0) | 0.541 | 3074 (51.1) | 597 (51.7) | 0.708 |
Maternal | ||||||
Maternal age (years), mean (SD) | 33.41 (3.80) | 31.91 (4.66) | <0.001 | 33.44 (4.43) | 32.82 (4.92) | <0.001 |
Maternal diabetes mellitus, n (%) | 238 (11.5) | 26 (9.1) | 0.221 | 597 (9.9) | 89 (7.7) | 0.019 |
Maternal hypertension, n (%) | 196 (9.5) | 22 (7.7) | 0.329 | 1749 (29.1) | 286 (24.8) | 0.003 |
Chorioamnionitis†, n (%) | 516 (29.9) | 63 (28.0) | 0.551 | 2084 (40.2) | 351 (37.0) | 0.064 |
Premature rupture of membrane, n (%) | 787 (38.1) | 84 (29.9) | 0.007 | 2334 (38.9) | 312 (27.5) | <0.001 |
Caesarean section, n (%) | 1837 (88.4) | 244 (85.3) | 0.132 | 4634 (77.1) | 807 (69.9) | <0.001 |
In vitro fertilisation, n (%) | 1152 (56.6) | 128 (45.1) | <0.001 | 494 (8.2) | 51 (4.4) | <0.001 |
Data are presented as mean (SD) or n (%).
*P value obtained from Χ2 test for categorical variables and Student’s t-test for continuous variables.
†Values were missing for 415 infants in the group of twins and 1039 infants in the group of singletons.
ACS, antenatal corticosteroid; SGA, small for gestational age.