Risk factors of cumulative colonisation with hospital and ESBL strains by week 4 (results of univariate regression analysis) at any site/material in family group
| Risk factor | Colonised | Not colonised | OR | 95% CI | P value | |
| n=24 (37.5%) | n=40 (62.5%) | |||||
| Colonisation with HAS | Intervention group (n= (%)) | 8 (25) | 24 (75) | 0.33 | 0.12 to 0.96 | 0.004 |
| BW* (g) | 1411 (1048–1624) | 1717 (1200–1956) | 0.88* | 0.78 to 0.99* | 0.031 | |
| GA (week) | 29.2 (27.4–31.2) | 31.4 (28.8–32.9) | 0.77 | 0.62 to 0.97 | 0.026 | |
| Colonisation with ESBL | n=(%) | 7 (10.9) | 57 (89.1) | |||
| BW* (g) | 1948 (1792.5–2355) | 1440 (1082–1856.8) | 1.28* | 1.04 to 1.57* | 0.022 | |
| MOBM % in TEF in first week (mL) | 95.9 (54.9–97.5) | 96.6 (90.7–100) | 0.96 | 0.93 to 1 | 0.036 | |
| TEF during hospital stay (mL/day) | 264.4 (238.2–306.5) | 187.2 (128.6–246.7) | 1.02 | 1 to 1.03 | 0.026 |
Values are presented as median (IQR).
*OR and 95% CI are calculated per 100 g of increase in BW, per 1 week of increase in GA, per mL increase for % of MOBM in TEF and per 1 mL/day increased in TEF.
BW, birth weight; ESBL, extended-spectrum beta-lactamases; GA, gestational age; HAS, hospital-acquired strain; MOBM, mother’s own breast milk; TEF, total enteral feeds.