Summary of schedule of procedures for intervention group
| Peanut OIT; intervention group | |||||||
| Study phase | Screening | Treatment | End of treatment | End of study | |||
| Week of study | Up to −24 | 0 | 2–12 | 16–48 | 52 (up to 56) | +4 from EOT | |
| Visit category | Screening visit | Entry OFC | Initiation | Updosing | Maintenance | Exit OFC | |
| Duration | 2 hours | 5–6 hours | 4 hours | 2–3 hours | 15 min remote | 5–6 hours | 15 min remote |
| Procedure | |||||||
| Informed consent | X | ||||||
| Eligibility criteria | X | X | X | ||||
| Demographics, medical and family history | X | ||||||
| Anthropometrics, vital signs, physical exam, SCORAD | X | X | X | X | X | ||
| Questionnaires | X | X—12 weeks | X—24 weeks | X | |||
| Skin prick test | X | X | |||||
| Blood, stool and saliva samples | X | (X) | X—12 weeks | X | |||
| Oral food challenge | X | X | |||||
| Adverse event, concomitant medication assessment | X | X | X | X | X | X | |
| Anaphylaxis education | X | X | X | X | |||
| OIT doses at site | X | X | |||||
| OIT dosing education | X | X | |||||
EOT, end of treatment; OFC, oral food challenge; OIT, oral immunotherapy; SCORAD, SCORing of Atopic Dermatitis.