Overview of the inclusion and exclusion criteria for saline treatment
| Inclusion criteria | Exclusion criteria |
| Hospitalisation due to symptoms of bronchiolitis* | Children with cystic fibrosis or other serious congenital chronic lung diseases |
| Age 0–12 months | Children in whom treatment with short-acting beta-2 agonist is initiated (as this is delivered in nebulised isotonic saline) |
| Parents provide informed consent for participation | Children who, after inclusion, are found to have a different acute lung disease than bronchiolitis |
| Children who, right at admission, need respiratory support in form of HFOT and CPAP |
*Runny nose, dry and persistent cough, laboured breathing (tachypnoea, retractions, nasal flaring), grunting, cyanosis or apnoea, wheezing or crackles on auscultation, O2 saturations below 92 %, difficulties feeding.
CPAP, continuous positive airway pressure; HFOT, high-flow oxygen therapy.