Cerebral blood flow profiles of infants with BM according to prognosis
| Acute phase (within 1 week, n=43) | Postacute phase (≥1 week, n=41) | |||||
| Sequelae (n=10) | No sequelae (n=33) | P | Sequelae (n=19) | No sequelae (n=22) | P value | |
| Age (days) | 27 (5–47) | 16 (3–30) | 0.41 | 44 (28–70) | 36 (16–58) | 0.23 |
| Days after onset | 4.00±1.76 | 4.64±1.52 | 0.27 | 18.11±5.57 | 13.41±6.05 | 0.01 |
| ACA-Vm, cm/s | 23.92±9.31 | 23.72±10.82 | 0.96 | 30.34±10.57 | 26.25±9.51 | 0.23 |
| ACA-S/D | 3.28 (2.68–4.01) | 3.62 (3.19–4.70) | 0.05 | 3.80 (3.10–5.18) | 4.00 (3.63–5.01) | 0.80 |
| ACA-RI | 0.70±0.07 | 0.74±0.07 | 0.05 | 0.75±0.08 | 0.75±0.06 | 0.86 |
| ACA-PI | 1.22±0.19 | 1.47±0.35 | 0.04 | 1.44±0.32 | 1.48±0.27 | 0.69 |
| MCA-Vm, cm/s | 36.77±8.25 | 29.95±7.71 | 0.07 | 45.50±15.14 | 29.47±7.73 | 0.02 |
| MCA-S/D | 3.39 (2.96–6.28 | 4.28 (3.29–5.20) | 0.52 | 4.13 (3.43–5.05) | 3.90 (3.42–4.47) | 0.90 |
| MCA-RI | 0.73±0.10 | 0.75±0.08 | 0.56 | 0.76±0.06 | 0.75±0.05 | 0.64 |
| MCA-PI | 1.41±0.38 | 1.57±0.40 | 0.40 | 1.60±0.34 | 1.46±0.34 | 0.35 |
Data are shown as means±SD or medians with IQRs.
*Days (n) after onset of BM when infants were assessed by cerebral ultrasound.
ACA, anterior cerebral artery; BM, bacterial meningitis; MCA, middle cerebral artery; PI, pulsatility index; RI, resistance index; S/D, ratio of maximum systolic and diastolic blood flow velocities; Vm, mean flow velocity.