Effect of proton pump inhibitors use in preterm infants
| Studies | Antacids | Control | P values* |
| Esomeprazole vs placebo | 25 infants | 26 infants | |
| Davidson et al 15 | |||
| Total number of GORD-related signs and symptoms, percentage of change from baseline after 14 days of treatment | −14.7% | 14.1% | 0.92 |
| Gastrointestinal events, percentage of change from baseline | −8.39% | 10.16% | 0.42 |
| Neurobehavioural events, percentage of change from baseline | −3.54% | −3.98% | 0.94 |
| Cardiorespiratory events, percentage of change from baseline | −38.94% | −41.17% | 0.89 |