Table 1

Baseline characteristics

VariablesPatients (n=161 386)
n (%)
Age group (years)
0–25332(3.30)
3–521 312(13.21)
6–949 079(30.41)
10–1221 026(13.03)
13–1964 637(40.05)
Gender
Male94 049(58.28)
Female67 337(41.72)
Season
Spring35 912(22.25)
Summer43 872(27.18)
Autumn47 157(29.22)
Winter34 445(21.34)
Concomitant medications*
Antihistamines117 113(72.57)
 Non-steroidal anti-inflammatory drugs89 518(55.47)
Corticosteroids76 684(47.52)
Histamine H2-receptor antagonists30 673(19.01)
Opioids18 773(11.63)
Benzodiazepines14 317(8.87)
Antipsychotics7865(4.87)
Psychostimulants7497(4.65)
Neuraminidase inhibitors6663(4.13)
Antiepileptics2732(1.69)
Antidepressants2222(1.38)
Neuropsychiatric adverse events
Anxiety disorder47 911(29.69)
Mood disorder46 114(28.57)
Personality disorder36 899(22.86)
Sleep-related disorder10 616(6.58)
Others10 194(6.32)
Movement disorder7076(4.38)
Psychotic disorder1469(0.91)
Cognitive disorder1087(0.67)
Self-harm20(0.01)
  • *Overalpped.