Table 1

Preoperative patient specific clinical variables and comorbidities by nutritional profile group

Preoperative clinical variablesUnderweight short n=656Overweight short n=733Underweight tall n=252Overweight tall n=1534Normal
n=26 862
P values*
Inpatient status585 (89.2)591 (80.6)210 (83.3)1142 (74.5)20 280 (75.5)<0.0001
Case status<0.0001
 Elective498 (76.0)411 (56.1)98 (38.9)1240 (80.8)14 431 (53.7)
 Urgent87 (13.3)151 (20.6)54 (21.4)124 (8.1)4851 (18.1)
 Emergent71 (10.9)171 (23.3)100 (39.7)170 (11.1)7580 (28.2)
Male gender405 (61.7)453 (61.8)156 (61.9)969 (63.2)14 911 (55.5)<0.0001
Race0.0003
 Caucasian491 (79.2)567 (81.9)185 (76.1)1240 (81.5)21 283 (83.8)
 African-American110 (17.7)105 (15.2)49 (20.2)239 (15.7)3289 (13.0)
 Asian18 (2.9)18 (2.6)9 (3.7)33 (2.2)661 (2.6)
 Native American1 (0.2)2 (0.3)08 (0.5)120 (0.5)
 Hispanic63 (9.6)132 (18.0)40 (15.9)199 (13.0)4054 (15.1)0.04
Age<0.0001
 29–364 days308 (47.0)225 (30.7)95 (37.7)840 (54.8)5069 (18.9)
 1–2 years32 (4.9)127 (17.3)13 (5.2)508 (33.1)1431 (5.3)
 3–5 years53 (8.1)122 (16.6)61 (24.2)24 (1.6)3007 (11.2)
 6–7 years32 (4.9)45 (6.1)36 (14.3)31 (2.0)2117 (7.9)
 8–12 years97 (14.9)114 (15.6)38 (15.1)83 (5.4)6980 (26.0)
 13–18 years134 (20.4)100 (13.6)9 (3.6)48 (3.1)8258 (30.7)
Premature birth170 (25.9)94 (12.8)14 (5.6)261 (17.0)2276 (8.5)<0.0001
Metabolic and nutritional conditions
 Nutritional support253 (38.6)139 (19.0)29 (11.5)286 (18.6)2515 (9.4)<0.0001
 Greater than 10% weight loss within 6 months286 (43.6)72 (9.8)37 (14.7)155 (10.1)1823 (6.8)<0.0001
Renal conditions
 Acute renal failure5 (0.8)3 (0.4)2 (0.8)11 (0.7)126 (0.5)0.27
American Society of Anesthesiologists class
 I33 (5.0)181 (24.7)74 (29.4)275 (17.9)7904 (29.4)<0.0001
 II147 (22.4)261 (35.6)111 (44.1)673 (43.9)12 044 (44.8)
 III407 (62.0)251 (34.2)59 (23.4)514 (33.5)6294 (23.4)
 IV65 (9.9)39 (5.3)6 (2.4)66 (4.3)591 (2.2)
 V4 (0.6)1 (0.1)2 (0.8)6 (0.4)29 (0.1)
Gastrointestinal conditions
 Oesophageal gastrointestinal disease436 (66.5)331 (45.2)100 (39.7)743 (48.4)8821 (32.8)<0.0001
 Hepatobiliary disease35 (5.3)36 (4.9)5 (2.0)76 (5.0)2321 (8.6)<0.0001
Cardiovascular conditions
 Cardiac risk factors<0.0001
  Mild cardiac risk factors103 (15.7)73 (10.0)5 (2.0)173 (11.3)1444 (5.4)
  Moderate cardiac risk factors55 (8.4)42 (5.7)6 (2.4)72 (4.7)693 (2.6)
  Severe cardiac risk factors26 (4.0)14 (1.9)1 (0.4)45 (2.9)280 (1.0)
 Cardiac surgery81 (12.4)56 (7.6)9 (3.6)127 (8.3)1086 (4.0)<0.0001
Neurological conditions
 Cerebrovascular accident42 (6.4)30 (4.1)5 (2.0)63 (4.1)509 (1.9)<0.0001
 Seizure disorder124 (18.9)65 (8.9)20 (7.9)72 (4.7)1110 (4.1)<0.0001
 Cerebral palsy112 (17.1)22 (3.0)8 (3.2)16 (1.0)516 (1.9)<0.0001
 Neuromuscular disorder77 (11.7)45 (6.1)12 (4.8)59 (3.9)844 (3.1)<0.0001
 Developmental delay263 (40.1)147 (20.1)26 (10.3)249 (16.2)2786 (10.4)<0.0001
 Central nervous system structural abnormality127 (19.4)75 (10.2)14 (5.6)156 (10.2)1296 (4.8)<0.0001
Haematological and immunological conditions
 Bleeding disorder11 (1.7)9 (1.2)0 (0)16 (1.0)223 (0.8)0.025
 Steroid use within 30 days37 (5.6)33 (4.5)4 (1.6)50 (3.3)918 (3.4)0.007
 Immune disease18 (2.7)18 (2.5)0 (0)19 (1.2)615 (2.3)0.69
 Haematological disorder64 (9.8)37 (5.1)8 (3.2)73 (4.8)1396 (5.2)0.001
 Bone marrow transplant4 (0.6)2 (0.3)06 (0.4)79 (0.3)0.33
 Transplantation4 (0.6)4 (0.6)03 (0.2)147 (0.6)0.61
 Preoperative red blood cell transfusion25 (3.8)19 (2.6)5 (2.0)23 (1.5)384 (1.4)<0.0001
Pulmonary conditions
 Asthma43 (6.6)70 (9.6)7 (2.8)81 (5.3)1665 (6.2)0.12
 Chronic lung disease92 (14.0)56 (7.6)5 (2.0)112 (7.3)856 (3.2)<0.0001
 Cystic fibrosis8 (1.2)4 (0.6)1 (0.4)7 (0.5)181 (0.7)0.52
 Structural pulmonary abnormality83 (12.7)64 (8.7)11 (4.4)130 (8.5)1078 (4.0)<0.0001
 Oxygen supplementation70 (10.7)53 (7.2)10 (4.0)96 (6.3)691 (2.6)<0.0001
 Tracheostomy18 (2.7)30 (4.1)3 (1.2)37 (2.4)264 (1.0)<0.0001
Acuity of condition
 Prior surgery within 30 days31 (4.7)22 (3.0)10 (4.0)39 (2.5)530 (2.0)<0.0001
 Open wound22 (3.4)13 (1.8)4 (1.6)40 (2.6)538 (2.0)0.07
 Cardiopulmonary resuscitation2 (0.3)3 (0.4)1 (0.4)2 (0.1)28 (0.1)0.006
 Do not resuscitate2 (0.3)001 (0.1)21 (0.1)0.35
 Inotropic support15 (2.3)7 (1.0)2 (0.8)11 (0.7)179 (0.7)<0.0001
 Preoperative sepsis within 48 hours<0.0001
  No sepsis620 (94.5)645 (88.0)205 (81.4)1452 (94.7)23 022 (85.7)
  Systemic inflammatory response syndrome17 (2.6)38 (5.2)16 (6.4)36 (2.4)1980 (7.4)
  Sepsis13 (2.0)47 (6.4)31 (12.3)39 (2.5)1799 (6.7)
  Septic shock6 (0.9)3 (0.4)0 (0)7 (0.5)61 (0.2)
  • *Derived from χ2 test of preoperative patient-specific clinical variables among nutritional profile groups.