Table 2

Ventilator settings, ventilation and transcutaneous blood gas values at baseline, presurfactant and at extubation time

Extubation Success GroupExtubation Failure GroupP values
Baseline
 MAP (cm H2O)10.2±1.110.2±1.00.94
 FiO2 0.40±0.170.48±0.240.08
 Amplitude (%)59±3356±320.72
 Frequency (Hz)9.6±1.09.7±0.80.69
 VT (mL/kg)1.6±0.61.5±0.50.51
 DCO2 (mL2/kg2/s)25±1525±101
 TcPO2 (mm Hg)53±1250±80.31
 TcPCO2 (mm Hg)52±854±40.30
Presurfactant
 MAP (cm H2O)13.1±1.611.9±2.40.02
 FiO2 0.25±0.010.33±0.08<0.001
 Amplitude (%)76±3062±310.08
 Frequency (Hz)9.3±1.09.6±0.90.30
 VT (mL/kg)1.9±0.61.8±0.40.52
 DCO2 (mL2/kg2/s)29±1529±101
 TcPO2 (mm Hg)59±1654±110.23
 TcPCO2 (mm Hg)46±950±40.08
Extubation
 MAP (cm H2O)6.1±0.96.1±1.20.97
 FiO2 0.22±0.030.23±0.020.30
 Amplitude (%)43±2439±120.46
 Frequency (Hz)9.3±1.29.3±0.70.88
 VT (mL/kg)2.1±0.61.9±0.60.28
 DCO2 (mL2/kg2/s)34±1135±150.70
 TcPO2 (mm Hg)56±554±30.08
 TcPCO2 (mm Hg)48±349±20.18
  • Values expressed as mean±SD.

  • DCO2, coefficient of gas transport; MAP, mean airways pressure; TcPCO2, transcutaneous PaO2 of CO2; TcPO2, transcutaneous PaO2 of O2.VT: tidal volume HFOV.