Characteristic | n (%) |
Sample size | |
Calculation reported | 155 (51.7) |
Recruitment target reached* | 102/145 (70.3) |
Recruitment delays reported | |
Yes | 19 (6.3) |
No | 281 (93.7) |
Types of recruitment delays† | |
Patient-level factors | 10/19 (52.6) |
Trial-level factors | 9/19 (47.4) |
Site-level factors | 1/19 (5.3) |
Trial-team-level factors | 1/19 (5.3) |
Not specified | 4/19 (21.1) |
How recruitment delays were addressed‡ | |
Stopping the trial before reaching the target | 13/19 (68.4) |
Extending the recruitment period | 3/19 (15.8) |
Modifying the eligibility criteria | 3/19 (15.8) |
Adding additional trial sites | 2/19 (10.5) |
Modifying incentives | 1/19 (5.3) |
*Based on sample size calculation and number randomised; data for this calculation were unavailable for 10 trials that reported a sample size calculation.
†Total exceeds 19 because some trials reported more than one type of delay.
‡Total exceeds 19 because some trials reported more than one method.