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Avascular necrosis of bone in neuroblastoma treated with combination chemotherapy

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Abstract

We treated two children with neuroblastoma and during the course of chemotherapy, avascular necrosis of the femoral head occurred. The main pathogenetic factor of this necrosis may be the toxic effect of cyclophosphamide.

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Abbreviations

VMA:

vanillylmandelic acid

HVA:

homovanillic acid

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Authors and Affiliations

  1. Department of Pediatrics, Faculty of Medicine, Kyushu University, Japan

    Eiichi Ishii, Nobuyuki Yoshida & Sumio Miyazaki

Authors
  1. Eiichi Ishii
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  2. Nobuyuki Yoshida
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  3. Sumio Miyazaki
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Ishii, E., Yoshida, N. & Miyazaki, S. Avascular necrosis of bone in neuroblastoma treated with combination chemotherapy. Eur J Pediatr 143, 152–153 (1984). https://doi.org/10.1007/BF00445806

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  • DOI: https://doi.org/10.1007/BF00445806

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