General Obstetrics and Gynecology: ObstetricsIntrauterine growth restriction increases morbidity and mortality among premature neonates
Section snippets
Material and methods
By using a database formed from a computer-assisted tool that generates clinical progress notes and discharge summaries on neonatal intensive care unit (NICU) admissions, we conducted a retrospective review to describe the outcomes of premature newborn infants cared for by Pediatrix Medical Group, Inc. Ten percent of fields in this database are periodically reviewed for data accuracy and previous audits have confirmed a greater than 98% accuracy in these selected fields. We compared newborn
Results
There are 121,774 records in our de-identified data set, 50,156 neonates had an estimated gestational age at delivery of 22 weeks or more and 34 weeks or less. We excluded 14,364 neonates who were products of pregnancies with multiple fetuses (ie, twins, triplets, or quadruplets), 25,967 neonates who were transported for care from an outside hospital, 1,303 neonates with congenital anomalies or chromosomal defects, and 68 patients with missing data on birth weight.
Our sample population included
Comment
In this article, we evaluated the impact of either a neonatal or antenatal diagnosis of IUGR on mortality and morbidity, using several different definitions. In our analyses, poor intrauterine growth at all gestational ages up to 32 weeks was associated with increased mortality and with serious morbidities often associated with adverse long-term problems. This and other recent studies contradict the notion that growth restriction may be associated with improved outcomes, presumably on the basis
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