The ratio of insulin to C-peptide can be used to make a forensic diagnosis of exogenous insulin overdosage

H Iwase; M Kobayashi; M Nakajima; T Takatori

doi:10.1016/s0379-0738(00)00298-x

The ratio of insulin to C-peptide can be used to make a forensic diagnosis of exogenous insulin overdosage

Forensic Sci Int. 2001 Jan 1;115(1-2):123-7. doi: 10.1016/s0379-0738(00)00298-x.

Authors

H Iwase¹, M Kobayashi, M Nakajima, T Takatori

Affiliation

¹ Department of Forensic Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. iwase@m.u-tokyo.ac.jp

PMID: 11056282
DOI: 10.1016/s0379-0738(00)00298-x

Abstract

A 25-year-old man was killed by his lover by an intravenous injection of insulin and then air. We had difficulty in determining whether insulin had really been injected, so we have 18 control cases and proved that the ratio of insulin to C-peptide in a corpse can be used as positive evidence for the insulin overdosage.

Publication types

Case Reports

MeSH terms

Adult
Autopsy / methods*
Blood Glucose / analysis
C-Peptide / blood*
Case-Control Studies
Cause of Death*
Embolism, Air / diagnosis
Homicide
Humans
Hypoglycemic Agents / blood*
Hypoglycemic Agents / poisoning*
Insulin / blood*
Insulin / poisoning*
Male
Toxicology / methods*

Substances

Blood Glucose
C-Peptide
Hypoglycemic Agents
Insulin