HIV-exposed uninfected infants are at increased risk for severe infections in the first year of life

J Trop Pediatr. 2012 Dec;58(6):505-8. doi: 10.1093/tropej/fms019. Epub 2012 May 3.

Abstract

HIV-exposed uninfected (HEU) infants have higher infectious morbidity than HIV-unexposed uninfected (HUU) infants. We present the clinical outcomes from a pilot cohort study of 27 HEU and 28 HUU infants. In the absence of infant malnutrition or advanced maternal HIV, HEU infants experienced a 2.74 (0.85-8.78) times greater risk of hospitalization in the first year.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Female
  • Follow-Up Studies
  • HIV Infections / epidemiology*
  • Hospitalization / statistics & numerical data*
  • Humans
  • Incidence
  • Infant
  • Infectious Disease Transmission, Vertical / statistics & numerical data*
  • Male
  • Morbidity
  • Odds Ratio
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology*
  • Respiratory Tract Infections / epidemiology
  • Risk Factors
  • Socioeconomic Factors
  • South Africa / epidemiology